VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Mouse

Scientific Name: Mus musculus

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Euarchontoglires-> Glires-> Rodentia-> Myomorpha-> Muroidea-> Muridae-> Murinae-> Mus-> Mus

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Human immunodeficiency virus 2

Family: Reoviridae

Receptor: CD4

Receptor CD4 information

Summary: This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_110001 2018.02 Microwell-seq Bladder Normal 2746 Link
Vthunter_110002 2018.02 Microwell-seq BoneMarrow Normal 510 Link
Vthunter_110003 2018.02 Microwell-seq BoneMarrowcKit Normal 5298 Link
Vthunter_110004 2018.02 Microwell-seq BoneMarrowcKit Normal 13019 Link
Vthunter_110005 2018.02 Microwell-seq BoneMarrowcKit Normal 8166 Link
Vthunter_110006 2018.02 Microwell-seq Brain Normal 3285 Link
Vthunter_110007 2018.02 Microwell-seq Brain Normal 753 Link
Vthunter_110008 2018.02 Microwell-seq EmbryonicMesenchymeE14.5 Normal 2771 Link
Vthunter_110011 2018.02 Microwell-seq Fetal Intestine Normal 6076 Link
Vthunter_110014 2018.02 Microwell-seq Fetal Stomach Normal 6192 Link
Vthunter_110015 2018.02 Microwell-seq Kidney Normal 4682 Link
Vthunter_110016 2018.02 Microwell-seq Liver Normal 4424 Link
Vthunter_110017 2018.02 Microwell-seq Liver Normal 261 Link
Vthunter_110018 2018.02 Microwell-seq Lung Normal 2512 Link
Vthunter_110019 2018.02 Microwell-seq Lung Normal 1414 Link
Vthunter_110020 2018.02 Microwell-seq Lung Normal 3014 Link
Vthunter_110021 2018.02 Microwell-seq MammaryGland.Involution Normal 3510 Link
Vthunter_110022 2018.02 Microwell-seq MammaryGland.Involution Normal 1311 Link
Vthunter_110023 2018.02 Microwell-seq MammaryGland.Lactation Normal 6633 Link
Vthunter_110024 2018.02 Microwell-seq MammaryGland.Lactation Normal 6905 Link
Vthunter_110025 2018.02 Microwell-seq MammaryGland.Pregnancy Normal 4909 Link
Vthunter_110026 2018.02 Microwell-seq MammaryGland.Virgin Normal 2081 Link
Vthunter_110027 2018.02 Microwell-seq MammaryGland.Virgin Normal 1059 Link
Vthunter_110028 2018.02 Microwell-seq MammaryGland.Virgin Normal 648 Link
Vthunter_110029 2018.02 Microwell-seq MammaryGland.Virgin Normal 1592 Link
Vthunter_110033 2018.02 Microwell-seq Muscle Normal 1102 Link
Vthunter_110034 2018.02 Microwell-seq NeonatalCalvaria Normal 4347 Link
Vthunter_110035 2018.02 Microwell-seq NeonatalCalvaria Normal 3617 Link
Vthunter_110036 2018.02 Microwell-seq NeonatalHeart Normal 3948 Link
Vthunter_110038 2018.02 Microwell-seq NeonatalMuscle Normal 4044 Link
Vthunter_110039 2018.02 Microwell-seq NeonatalPancreas Normal 4571 Link
Vthunter_110040 2018.02 Microwell-seq NeonatalRib Normal 1217 Link
Vthunter_110041 2018.02 Microwell-seq NeonatalRib Normal 3082 Link
Vthunter_110042 2018.02 Microwell-seq NeonatalRib Normal 1963 Link
Vthunter_110043 2018.02 Microwell-seq NeonatalSkin Normal 3392 Link
Vthunter_110044 2018.02 Microwell-seq Ovary Normal 1931 Link
Vthunter_110045 2018.02 Microwell-seq Pancreas Normal 3610 Link
Vthunter_110046 2018.02 Microwell-seq PeripheralBlood Normal 3201 Link
Vthunter_110047 2018.02 Microwell-seq PlacentaE14.1 Normal 1873 Link
Vthunter_110048 2018.02 Microwell-seq PlacentaE14.2 Normal 2473 Link
Vthunter_110049 2018.02 Microwell-seq Prostate Normal 1031 Link
Vthunter_110051 2018.02 Microwell-seq SmallIntestine Normal 3438 Link
Vthunter_110052 2018.02 Microwell-seq SmallIntestine Normal 1671 Link
Vthunter_110053 2018.02 Microwell-seq SmallIntestine Normal 1575 Link
Vthunter_110054 2018.02 Microwell-seq Spleen Normal 1970 Link
Vthunter_110055 2018.02 Microwell-seq Stomach Normal 2389 Link
Vthunter_110056 2018.02 Microwell-seq Testis Normal 2216 Link
Vthunter_110057 2018.02 Microwell-seq Testis Normal 11789 Link
Vthunter_110058 2018.02 Microwell-seq TrophoblastStemCells Normal 19489 Link
Vthunter_110059 2018.02 Microwell-seq Uterus Normal 2035 Link
Vthunter_110060 2018.02 Microwell-seq Uterus Normal 1704 Link
Vthunter_110066 2019.12 MARS-seq TotalBrain Normal 2304 Link
Vthunter_110101 2020.09 10X Genomics Teeth Teeth 2888 Link
Vthunter_110105 2018.07 10X Genomics Adipose Adipose 288 Link
Vthunter_110106 2016.02 10X Genomics PrimaryVisualCortex PrimaryVisualCortex 1787 Link
Vthunter_110107 2019.03 10X Genomics CardiacVentricle CardiacVentricle 121 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of CD4 in human tissues   [NCBI]

Expression: Broad expression in spleen (RPKM 82.4), lymph node (RPKM 55.1) and 19 other tissues

Protein expression of CD4 in human tissues   [Proteinatlas]